Table 1.

IC₅₀ values, μg/mL (μM). “-”—50% inhibition is not achieved in the concentration range of 0–160 μg/mL.

Peptide	Classical Pathway Model			Alternative Pathway Model
	C3a	C5a	Hemolysis	C3a	C5a	Hemolysis
Ar-1[V8R]	43.4 (15.4)	2.1 (0.75)	8.9 (3.2)	129.6 (46.0) *	78.7 (28.0)	67.0 (23.8)
ALP1	57.3 (25.1) *	79.2 (34.7) *	61.4 (26.9) *	123.7 (54.2) *	98.8 (43.3)	90.5 (39.6)
AA139	140.2 (55.0)	141.4 (55.5)	130.6 (51.2)	-	-	-

* Bidirectional action was observed with signal enhancement at lower concentrations.