Table 1.
Baseline Characteristics.
| Variable | FMR N = 148 (%) |
DMR N = 60 (%) |
p Value |
|---|---|---|---|
| Age | 77.2 ± 8.4 | 80.2 ± 7.2 | 0.02 |
| Gender-Female | 47 (31.8) | 19 (31.7) | 0.26 |
| BMI | 25.4 ± 3.1 | 26.1 ± 4.2 | 0.21 |
| Hemoglobin (g/dL) | 11.6 ± 1.7 | 12.2 ± 1.2 | 0.11 |
| GFR (mL/min) | 58.4 ± 27.2 | 58.1 ± 20.1 | 0.36 |
| Hypertension | 118 (79.8) | 38 (63.3) | 0.42 |
| Diabetes Mellitus | 71 (48.0) | 21 (35.0) | 0.27 |
| Dyslipidemia | 101 (68.2) | 43 (71.7) | 0.10 |
| Smoking | 38 (25.7) | 26 (43.3) | 0.31 |
| COPD | 24 (16.2) | 11 (18.3) | 0.23 |
| Stroke (CVA or TIA) | 36 (24.3) | 8 (13.3) | 0.09 |
| Coronary Artery disease | 80 (54.1) | 6 (10.0) | 0.02 |
| Cardiac Surgery | 47 (31.8) | 6 (10.0) | 0.09 |
| Atrial Fibrillation/Flutter | 105 (70.9) | 23 (38.3) | 0.02 |
| Pacemaker | 31 (20.9) | 13 (21.7) | 0.41 |
| Oncologic disease | 17 (11.5) | 12 (20.0) | 0.12 |
| Previous MitraClip | 4 (2.7) | 1 (1.7) | 0.22 |
| Peripheral pitting edema | 21 (14.2) | 9 (15.0) | 0.34 |
| NYHA class - no. (%) | 0.18 | ||
| II | 42 (28.4) | 21 (35.0) | |
| III | 60 (40.5) | 23 (38.3) | |
| IV | 46 (31.1) | 16 (26.7) | |
| STS score- for MV repair mortality | 5.8 ± 4.1 | 5.4 ± 3.3 | 0.37 |
| Medications | |||
| Antiplatelets | 67 (45.3) | 20 (33.3) | 0.12 |
| Anticoagulants | 38 (25.7) | 19 (31.7) | 0.29 |
| ACEi/ARB | 100 (67.6) | 41 (68.3) | 0.32 |
| Beta blockers | 126 (85.1) | 47 (78.3) | 0.39 |
| MRA | 42 (28.4) | 12 (20.0) | 0.42 |
Values are mean ± SD or n (%). Abbreviations: FMR, functional mitral regurgitation; DMR, degenerative mitral regurgitation; BMI, body mass index; GFR, glomerular filtration rate; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; TIA, transient ischemic attack; NYHA, New York heart association; STS, society of thoracic surgery; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; MRA, mineralocorticoid receptor antagonist.