Table 4.
Clinical outcome of COVID-19 patients from 2022, comparing those with the highest OHP quartile to the lowest OHP quartile. Data are n (%), and median (interquartile range, IQR), unless specified otherwise.
| OHP Quartile 1 | OHP Quartile 4 | p-Value | |
|---|---|---|---|
| n | 67 | 65 | |
| Age (years) | 73.0 (47.0, 84.0) | 72.0 (61.0, 79.0) | 0.61 * |
| Male | 30 (44.8%) | 37 (56.9%) | 0.16 |
| D-dimer (mg/L FEU) | 2.28 | 2.94 | 0.001 * |
| Fully vaccinated | 59 (88.1%) | 43 (66.2%) | 0.003 |
| Days from symptom onset to admission | 3.0 (1.0, 6.0) | 7.0 (3.0, 11.0) | <0.001 |
| Weight (kg) | 74.5 (62.2, 87.5) | 78.2 (68.0, 100.0) | 0.032 * |
| Venous thrombosis | 1 (1.5%) | 1 (1.5%) | 0.98 |
| Arterial thrombosis | 4 (6.0%) | 2 (3.1%) | 0.42 |
| Oxygen requiring | 23 (34.3%) | 50 (76.9%) |
<0.001
(OR: 1.84 (95%CI 1.42–2.37)) |
| Intensive care unit | 7 (10.4%) | 9 (13.8%) | 0.55 |
| Inotropes | 5 (7.5%) | 1 (1.6%) | 0.11 |
| Assisted ventilation | 9 (13.4%) | 27 (41.5%) |
<0.001
(OR: 1.65 (95%CI 1.24–2.21)) |
| Deterioration | 13 (19.4%) | 27 (41.5%) |
0.006
(OR: 1.41 (95%CI 1.09–1.84)) |
| Death from COVID-19 | 3 (4.7%) | 5 (8.1%) | 0.44 |
Abbreviations: OHP, overall hemostatic potential; OR, odds ratio * p-values adjusted for sex; boldened values signify p < 0.05.