Skip to main content
. 2022 Sep 21;8(10):992. doi: 10.3390/jof8100992

Table 1.

Overview of genes targeted in the single target CRISPR/Cas experiments. “Name” denotes the gene names used in this study and are underlined if they relate to the homologous gene in Saccharomyces cerevisiae.

Locus Tag Name Potential Function/Role References
ACIB2EUKG769938 BGS5 Heavy chain dynein [52]
ACIB2EUKG768596 BGS7 Pleckstrin-like, nuclear transport [52]
ACIB2EUKG769034 BGS12 Cytoplasmic dynein, intermediate chain [52]
ACIB2EUKG770622 BGS13 (PKC1) Pc1 kinase, a protein serine/threonine kinase, which controls a highly conserved signaling pathway managing cell wall integrity [51,52,53,54]
ACIB2EUKG771351 MSG5 Dual-specificity protein phosphatase (i.e., Ser/Thr- and Tyr-specific), which plays a role in the regulation of at least two mitogen-activated protein kinase (MAPK)-mediated pathways [55]
ACIB2EUKG771893 YPK1 Ser/Thr-protein kinase and is a relevant part of sphingolipid-mediated and cell integrity signaling pathways [55,56]
ACIB2EUKG770030 FKS1 1,3-beta-D-glucan synthase, therefore being responsible for the synthesis of the polysaccharide, which is the main structural component of the cell wall [57]
ACIB2EUKG771759 ROM2 One of three guanine nucleotide exchange factors probably specific to Rho1p and Rho2p [55]
ACIB2EUKG772498 NCE102 Integral membrane protein, being involved in an alternative pathway for protein export [58,59]
HHS Vulnerability Disclosure