Table 2.
Descriptive and clinical characteristics by physical component summary of SF-36.
| Overall n = 158 |
PCS ≤ 50 n = 89 |
PCS > 50 n = 69 |
p-Value | |
|---|---|---|---|---|
| Demographics | ||||
| Age (years), mean ± SD | 52 ± 17 | 52 ± 17 | 51 ± 17 | 0.62 |
| Female sex | 85 (54%) | 49 (55%) | 36 (53%) | 0.92 |
| BMI, (kg/m2), median (IQR) | 26.2 (5.7) | 26.4 (7.2) | 25.9 (4.9) | 0.32 |
| Systolic blood pressure (mmHg), median (IQR) | 120 (16) | 120 (20) | 115 (10) | 0.07 |
| Diastolic Blood pressure (mmHg), median (IQR) | 70 (15) | 70 (15) | 70 (11) | 0.56 |
| Smoking | 11 (8.0%) | 4 (4.9%) | 7 (13%) | 0.12 |
| Atrial arrhythmia | 1 | |||
| Atrial fibrillation | 101 (77%) | 61 (77%) | 40 (77%) | |
| Atrial flutter | 20 (15%) | 12 (15%) | 8 (15%) | |
| Intra-atrial reentry tachycardia | 10 (7.6%) | 6 (7.6%) | 4 (7.7%) | |
| Pattern of arrhythmia | 0.4 | |||
| First diagnosed | 10 (7.9%) | 5 (6.6%) | 5 (10%) | |
| Paroxysmal | 73 (58%) | 43 (57%) | 30 (60%) | |
| Persistent | 7 (5.6%) | 3 (3.9%) | 4 (8.0%) | |
| Permanent | 36 (29%) | 25 (33%) | 11(22%) | |
| Medical history | ||||
| Major bleeding | 5 (3.6%) | 2 (2.4%) | 3 (5.5%) | 0.38 |
| Clinically relevant non-major bleeding | 19 (14%) | 14 (17%) | 5 (9.1%) | 0.30 |
| Minor bleeding | 41 (31%) | 29 (36%) | 12 (23%) | 0.13 |
| Thromboembolism | 3 (2.2%) | 2 (2.5%) | 1 (1.8%) | 1 |
| Dyslipidemia | 26 (19%) | 17 (21%) | 9 (16%) | 0.51 |
| Hypertension | 40 (29%) | 26 (32%) | 14 (25%) | 0.48 |
| Diabetes | 22 (16%) | 14 (17%) | 8 (15%) | 0.92 |
| Heart failure | 74 (54%) | 48 (59%) | 26 (46%) | 0.14 |
| Chronic kidney disease | 9 (6.5%) | 6 (7.1%) | 3 (5.6%) | 1 |
| NT-proBNP (pg/mL), median (IQR) | 756 (1611) | 725 (1585) | 924 (1020) | 0.34 |
| NYHA functional class | <0.001 | |||
| 1 | 44 (33%) | 15 (18%) | 29 (59%) | |
| 2 | 59 (45%) | 44 (53%) | 15 (31%) | |
| 3 | 26 (20%) | 21 (25%) | 5 (10%) | |
| 4 | 3 (2.3%) | 3 (3.6%) | 0 (0%) | |
| Stroke–bleeding risk | ||||
| CHA2DS2-VASc score, median (IQR) | 2 (1) | 2 (2) | 1 (1) | 0.07 |
| HAS-BLED score, median (IQR) | 1 (1.75) | 1 (2) | 1 (1) | 0.07 |
| Echocardiography | ||||
| Systemic ventricular fraction (%), median (IQR) | 53 (8) | 50 (8) | 55 (12) | 0.07 |
| LA diameter (cm), median (IQR) | 4.45 (1.15) | 4.50 (0.77) | 4.30 (1.20) | 0.15 |
| Electrocardiogram | ||||
| QRS, median (IQR) | 110 (25) | 109 (30) | 116 (22) | 0.34 |
| Health status metrics | ||||
| mEHRA score, mean ± SD | 1.24 ± 1.07 | 1.33 ± 1.13 | 1.10 ± 0.98 | 0.20 |
| Medication | ||||
| Class I antiarrhythmic | 10 (6.3%) | 4 (4.5%) | 6 (8.7%) | 0.3 |
| Class III antiarrhythmic | 41 (26%) | 23 (26%) | 18 (26%) | 1 |
| beta-blocker | 82 (60%) | 52 (65%) | 30 (54%) | 0.2 |