Table 3.
Descriptive and clinical characteristics by mental component summary of SF-36 Health Survey.
| Overall N = 158 |
MCS ≤ 50 N = 89 |
MCS > 50 N = 69 |
p-Value | |
|---|---|---|---|---|
| Demographics | ||||
| Age (years), mean ± SD | 52 (17) | 52 (17) | 51 (17) | 0.77 |
| Female sex | 85 (54%) | 39 (51%) | 46 (57%) | 0.48 |
| BMI, (kg/m2), median (IQR) | 26.2 (5.7) | 26.6 (5.7) | 26.0 (5.1) | 0.49 |
| Systolic blood pressure (mmHg), median (IQR) | 120 (16) | 120 (20) | 120 (14) | 0.30 |
| Diastolic Blood pressure (mmHg), median (IQR) | 70 (15) | 70 (15) | 70 (14) | 0.88 |
| Smoking | 11 (8.0%) | 5 (7.1%) | 6 (9.0%) | |
| Atrial arrhythmia | 0.37 | |||
| Atrial fibrillation | 101 (77%) | 53 (82%) | 48 (73%) | |
| Atrial flutter | 20 (15%) | 7 (11%) | 13 (20%) | |
| Intra-atrial reentry tachycardia | 10 (7.6%) | 5 (7.7%) | 5 (7.6%) | |
| Pattern of arrhythmia | 0.28 | |||
| First diagnosed | 10 (7.9%) | 4 (6.6%) | 6 (9.2%) | |
| Paroxysmal | 73 (58%) | 43 (57%) | 30 (60%) | |
| Persistent | 7 (5.6%) | 3 (3.9%) | 4 (8.0%) | |
| Permanent | 36 (29%) | 25 (33%) | 11 (22%) | |
| Medical history | ||||
| Major bleeding | 5 (3.6%) | 1 (1.4%) | 4 (5.8%) | 0.21 |
| Clinically relevant non-major bleeding | 19 (14%) | 8 (12%) | 11 (16%) | 0.62 |
| Minor bleeding | 41 (31%) | 24 (35%) | 17 (26%) | 0.34 |
| Thromboembolism | 3 (2.2%) | 2 (3.0%) | 1 (1.4%) | 0.62 |
| Dyslipidemia | 26 (19%) | 13 (19%) | 13 (19%) | 1 |
| Hypertension | 40 (29%) | 24 (35%) | 16 (24%) | 0.15 |
| Diabetes | 22 (16%) | 13 (18%) | 9 (13%) | 0.56 |
| Heart failure | 74 (54%) | 43 (61%) | 31 (46%) | 0.08 |
| Chronic kidney disease | 9 (6.5%) | 7 (9.9%) | 2 (3.0%) | 0.17 |
| NT-proBNP (pg/mL), median (IQR) | 756 (1611) | 642 (1131) | 782 (1756) | 0.61 |
| NYHA functional class | 0.16 | |||
| 1 | 44 (33%) | 18 (25%) | 26 (43%) | |
| 2 | 59 (45%) | 34 (48%) | 25 (41%) | |
| 3 | 26 (20%) | 17 (24%) | 9 (15%) | |
| 4 | 3 (2.3%) | 2 (2.8%) | 1 (1.6%) | |
| Stroke–bleeding risk | ||||
| CHA2DS2-VASc score, median (IQR) | 2 (1) | 2 (2) | 1 (1) | 0.04 |
| HAS-BLED score, median (IQR) | 1 (1.75) | 1 (2) | 1 (1) | 0.31 |
| Echocardiography | ||||
| Systemic ventricular fraction (%), median (IQR) | 53 (8) | 54 (8) | 53 (7) | 0.78 |
| LA diameter (cm), median (IQR) | 4.45 (1.15) | 4.55 (1.20) | 4.30 (1.00) | 0.31 |
| Electrocardiogram | ||||
| QRS, Median (IQR) | 110 (25) | 114 (32) | 110 (20) | 0.79 |
| Health status metrics | ||||
| mEHRA score, mean ± SD | 1.24 ± 1.07 | 1.41 ± 1.47 | 1.06 ± 0.97 | 0.05 |
| Medication | ||||
| Class I antiarrhythmic | 10 (6.3%) | 4 (5.2%) | 6 (7.4%) | 0.75 |
| Class III antiarrhythmic | 41 (26%) | 20 (26%) | 21 (26%) | 1 |
| beta-blocker | 82 (60%) | 41 (59%) | 41 (61%) | 0.8 |
BMI, body mass index; CHA2DS2-Vasc (Congestive heart failure, Hypertension, Age ≥ 75 years, Diabetes mellitus, Stroke/transient ischemic attack, Vascular disease, Age 65 to 74 years, Sex category); HAS-BLED (Hypertension, Abnormal renal/ liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/alcohol); IQR, interquartile range; LA, left atrium; mEHRA, modified European Heart Rhythm Association; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; NYHA, New York Heart Association; SD, standard deviation; SF-36, Short Form-36.