Table 1.
1H (700 MHz) and 13C (175 MHz) NMR data of compounds 1–3 (DMSO-d6, δ in ppm).
| Position | 1 | 2 | 3 | ||||
|---|---|---|---|---|---|---|---|
| δC, Type | δH, (J in Hz) | δH, (J in Hz) a | δC, Type | δH, (J in Hz) | δC, Type | δH, (J in Hz) | |
| 2 | 144.8, C | 144.7, C | 144.7, C | ||||
| 4 | 125.5, C | 125.5, C | 125.5, C | ||||
| 5 | 125.5, C | 125.5, C | 125.5, C | ||||
| 6 | 23.8, CH2 | 2.41, t (8.0) | 2.20, m | 23.8, CH2 | 2.40, t (7.8) | 23.7, CH2 | 2.30, t (8.1) |
| 7 | 20.6, CH2 | 1.34, m | 1.25, m | 20.6, CH2 | 1.34, m | 20.5, CH2 | 1.29, m |
| 8 | 13.3, CH3 | 0.80, t (7.3) | 0.69, t (7.3) | 13.3, CH3 | 0.80, t (7.2) | 13.2, CH3 | 0.71, t (7.3) |
| 9 | 7.9, CH3 | 2.15, s | 2.03, s | 7.9, CH3 | 2.13, s | 8.0, CH3 | 2.22, s |
| 10 | 8.0, CH3 | 2.20, s | 2.10, s | 8.0, CH3 | 2.19, s | 8.0, CH3 | 2.22, s |
| 1′ NH | 11.11, s | 10.80, s | 11.02, s | 11.03, s | |||
| 2′ | 123.9, CH | 7.17, s b | 7.02, s b | 123.8, CH | 7.16, s | 123.8, CH | 7.16, s |
| 3′ | 109.1, C | 109.1, C | 109.1, C | ||||
| 4′ | 126.8, C | 126.8, C | 126.8, C | ||||
| 5′ | 117.5, CH | 7.39, d (7.3) | 7.27, d (7.9) | 117.5, CH | 7.40, d (7.9) | 117.5, CH | 7.38, m |
| 6′ | 118.6, CH | 7.00, t (7.7) | 6.93, d (7.5) | 118.6, CH | 7.00, t (7.4) | 118.6, CH | 7.01, t (7.5) |
| 7′ | 121.2, CH | 7.09, t (7.5) | 7.02, m b | 121.2, CH | 7.09, t (7.4) | 121.2, CH | 7.09, t (7.5) |
| 8′ | 111.6, CH | 7.38, d (7.6) | 7.32, d (8.1) | 111.6, CH | 7.38, d (8.0) | 111.6, CH | 7.38, m |
| 9′ | 136.1, C | 136.1, C | 136.1, C | ||||
| 10′ | 25.0, CH2 | 3.08, t (7.0) | 3.03, t (6.8) | 25.0, CH2 | 3.07, t (6.7) | 24.9, CH | 2.95, t (7.2) |
| 11′ | 45.8, CH2 | 4.30, t (7.0) | 4.21, t (6.7) | 45.7, CH2 | 4.29, t (6.7) | 45.6, CH | 4.23, t (7.3) |
| 1″ c | 136.8, C | 126.7, C | 11.03, s | ||||
| 2″ | 128.9, CH | 7.16, m b | 7.02, m b | 129.9, CH | 6.91, d (7.9) | 123.8, CH | 7.16, s |
| 3″ | 128.6, CH | 7.32, t (7.3) | 7.21, m | 115.3, CH | 6.70, d (8.0) | 109.1, C | |
| 4″ | 127.0, CH | 7.28, m | 7.17, m | 156.5, C | 126.8, C | ||
| 5″ | 128.6, CH | 7.32, t (7.3) | 7.21, m | 115.3, CH | 6.70, d (8.0) | 117.5, CH | 7.38, m |
| 6″ | 128.9, CH | 7.16, m b | 7.02, m b | 129.9, CH | 6.91, d (7.9) | 118.6, CH | 7.01, t (7.5) |
| 7″ | 35.0, CH2 | 2.80, t (7.5) | 2.70, t (7.3) | 34.2, CH2 | 2.69, t (6.9) | 121.2, CH | 7.09, t (7.5) |
| 8″ | 45.8, CH2 | 4.22, t (7.5) | 4.09, t (7.2) | 46.2, CH2 | 4.14, t (6.9) | 111.6, CH | 7.38, m |
| 9″ | 136.1, C | ||||||
| 10″ | 24.9, CH | 2.95, t (7.2) | |||||
| 11″ | 45.6, CH | 4.23, t (7.3) | |||||
a 1H NMR data of compound 1 with TFA added. b Signals overlapped. c NH at 1″ for compound 3.