Figure 1.

Baseline concentration and prognostic utility of host biomarkers in participants with moderate coronavirus disease 2019. A, Concentrations plotted on log₂ scale and expressed in pg/mL (Ang-2, CXCL-10, IL-1ra, IL-6, IL-8, IL-10, PCT, sTREM-1), ng/mL (D-dimer, suPAR), mg/L (CRP), or × 10⁹ cells/L (platelets). B, Biomarkers ordered from left to right by ascending mean c-statistic across the 3 severity outcomes. Abbreviations: Ang-2, angiopoietin-2; AUC, area under the receiver operating characteristic curve; CRP, C-reactive protein; IL, interleukin; MV, mechanical ventilation; NIV, noninvasive ventilation; NLR, neutrophil-to-lymphocyte ratio; O₂, oxygen; PCT, procalcitonin; sTREM-1, soluble triggering receptor expressed on myeloid cells 1; suPAR, soluble urokinase plasminogen activator receptor.