Table 2.
Risk of Bias Assessment of Included Studies.
| Study | Item 1 | Item 2 | Item 3 | Item 4 | Item 5 | Item 6 | Item 7 | Item 8 | Item 9 | Item 10 | Item 11 | Item 12 | Item 13 | Item 14 | Item 15 | Overall |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asadi-Golshan, 2018 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Low |
| Borhani-Haghighi, 2020 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | ✓ | ✓ | NR | High |
| Cantinieaux, 2013 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | Low |
| Chen, 2019 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | Low |
| Chudickova, 2019 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | Low |
| Cizkova, 2018 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | ✓ | ✓ | NR | High |
| Gu, 2017 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | Low |
| Kaneliyo, 2018 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | ✓ | ✓ | ✓ | NR | Some concern |
| Khoshsirat, 2018 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | Low |
| Tsai, 2019 | ✓ | ✓ | ✓ | ✓ | NR | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | Some concern |
| Yeng, 2016 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | NR | Low |
1. Species; 2. Using appropriate tests; 3. Severity of injury; 4. Level of injury; 5. Age/weight; 6. Number of animals per group; 7. Designation of strain; 8. Definition of control; 9. Description of statistical analysis; 10. Regulation and ethics; 11. Bladder expression; 12. Blindness of assessor; 13. Genetic background; 14. Method of allocation to treatments; 15. Description of the reasons to exclude animals from the experiment during the study (attrition).
✓: Low risk of bias; NR: Not reported