Table 1.
Similar peptides between SARS-CoV-2 SP and H. sapiens proteins with extracellular domains.
| UniProt ID | Protein-Gene | Position | Range of extracellular amino acids | Sequences similar to SARS-CoV-2 SP (pentapeptides and hexapeptides) |
Localization in SP subunit |
Pentapeptides/hexapeptides in other CoVs | B cell neutralizing antibody epitopes (Fig. 9) | Experimental evidence, ID in IEBD |
|---|---|---|---|---|---|---|---|---|
| P32004 (*) | Neural cell adhesion molecule L1- L1CAM |
1 | 20–1120 | DLQELG | S2 | (SARS-CoV) | LNEVAKNLNESLIDLQELGK | 1,309,518 (in vivo admin) |
| P23471 (*) | Receptor-type tyrosine-protein phosphatase zeta-PTPRZ1 | 2 | 25–1636 | SASFST/Iso3 | S1 and RBD | |||
| 3 | 25–1636 | AVLYQ | S1 | (SARS-CoV) | ||||
| 4 | 25–1636 | SQILP | S2 | (SARS-CoV) | PIKDFGGFNFSQILPDPSKP | 1334475;133 4476 | ||
| 5 | 25–1636 | SASFS/iso3 | S1 and RBD | |||||
| 6 | 25–1636 | ASFST/iso3 | S1 and RBD | |||||
| Q6N022 (*) | Teneurin-4-TENM4 | 7 | 367–2769 | GTTLD | S1 | |||
| 8 | 367–2769 | LLAGT | S2 | |||||
| 9 | 367–2769 | QIITT | S2 | (SARS-CoV) | QRNFYEPQIITTDNT | 1,310,750 | ||
| 10 | 367–2769 | VAIHA | S1 | |||||
| 11 | 367–2769 | RLFRK | S1 and RBD | NLDSKVGGNYNYLYRLFRK SN |
1,330,538 | |||
| P04626 (*) | Receptor tyrosine-protein kinase erbB-2- ERBB2 |
12 | 23–652 | PLQPE/iso2,3 | S2 | (SARS-CoV) | ||
| P20702 (*) | Integrin alpha-X-ITGAX | 13 | 20–1107 | DVVIG | S2 | (SARS-CoV) | ||
| O75882 (*) | Attractin-ATRN | 14 | 84–1279 | FGGFN | S2 | (SARS-CoV) | PIKDFGGFNFSQILPDPSKP | 1334475; 1,334,476 |
| P05556 (**) | Integrin beta-1-ITGB1 | 15 | 21–728 | GEVFN | S1 and RBD | (SARS-CoV) | ||
| P20916 (**) | Myelin-associated glycoprotein - MAG |
16 | 20–516 | PPLLT | S2 | (SARS-CoV) | ||
| *Global search result for H. Sapiens ** Network results obtained for PMP22 in STRING /pentapeptide or hexapeptide that is not present in any isoform | ||||||||