FIG. 1.

Body temperature and circulating levels of TNF-α and sTNFR-I during human endotoxemia in young versus elderly subjects. Changes in body temperature from baseline in elderly subjects (n = 9) and young controls (n = 8) are shown at the top. Averages and 95% confidence intervals are shown. Concentrations of TNF-α in young (n = 8) and elderly (n = 8); subjects and concentrations of sTNFR-I in young (n = 8), elderly (n = 8) subjects are shown below. Geometric means and 95% confidence intervals are shown. ∗, significant difference between age groups in the changes from baseline values (p < 0.05).