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. 2022 Oct 19;2022:3067526. doi: 10.1155/2022/3067526

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Copyright © 2022 Mi-Rae Shin et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The representative images and quantitative evaluation of Safranin-O staining (magnification x200) (a) and micro-computed tomography (b) Normal: normal rats; Control: MIA-induced osteoarthritis rats; INDO : MIA-induced osteoarthritis rats administered indomethacin (2 mg/kg body weight); 5-Loxin® 100: MIA-induced osteoarthritis rats administered 5-Loxin® (100 mg/kg body weight); 5-Loxin® 200: MIA-induced osteoarthritis rats administered 5-Loxin® 200 mg/kg body weight. Significance: ^##p < 0.01vs. normal rat values and ^∗p < 0.05, ^∗∗p < 0.01vs. MIA control rat values.