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. 2022 Aug 11;49(13):4440–4451. doi: 10.1007/s00259-022-05926-2

Table 1.

Absorbed doses and extrapolated cumulative absorbed doses (Gy) in the main organs of mice injected with 1 × and 3 × [177Lu]Lu-NeoB, respectively

40 MBq/400 pmol (M) 80 MBq/800 pmol (M) 120 MBq/1200 pmol (M) 120 MBq/1200 pmol (F)
Times injected: 1 ×  3 ×  1 ×  3 ×  1 ×  3 ×  1 ×  3 × 
Adrenal glands 0.58 1.74 0.54 1.62 0.66 1.99 0.82 2.47
Brain 0.05 0.15 0.12 0.36 0.15 0.44 0.12 0.35
Heart wall 0.25 0.75 0.46 1.38 0.68 2.03 0.42 1.27
Kidneys 2.00 6.00 3.25 9.75 3.21 9.62 5.24 15.71
Liver 2.11 6.33 3.28 9.84 5.61 16.84 4.37 13.11
Colon wall 0.81 2.43 1.21 3.63 0.93 2.80 1.81 5.43
Lungs 0.35 1.05 0.87 2.61 3.91 11.72 0.62 1.87
Mammary fat pad 0.27 0.81 0.23 0.69 0.49 1.47 1.11 3.34
Osteogenic cells 0.03 0.09 0.06 0.18 0.12 0.37 0.07 0.21
Ovaries - - - - - - 0.53 1.60
Pancreas 2.23 6.69 2.31 6.93 1.54 4.61 3.30 9.89
Prostate gland 0.35 1.05 0.68 2.04 0.37 1.10 - -
Small intestine 0.80 2.40 1.21 3.63 0.94 2.81 1.80 5.40
Spleen 0.50 1.50 0.72 2.16 1.35 4.05 0.68 2.05
Stomach wall 1.50 4.50 1.50 4.50 1.38 4.14 1.31 3.94
Testes 0.02 0.06 0.04 0.12 0.08 0.23 - -
Total body 0.31 0.93 0.47 1.41 0.66 1.97 0.65 1.95
Urinary bladder 0.02 0.06 0.04 0.12 0.08 0.24 0.05 0.15