Fig. 1.

Associations between GFAP biomarkers and CSF Aβ. This figure shows the associations between plasma GFAP and CSF GFAP for all subjects (A) and by AT stages (B). β and p values shown in (B) correspond to the interaction effect between tau-negative (A-T- and A + T-) and tau-positive (A + T +) groups. AT groups were derived from previously published thresholds on CSF Aβ42/40 and CSF p-tau [1]. Abbreviations: Aβ, amyloid-β; A-T-, Aβ-negative tau-negative; A + T-, Aβ-positive tau-negative; A + T + , Aβ-positive tau-positive; CSF, cerebrospinal fluid; GFAP, glial fibrillary acidic protein; p-tau, phosphorylated tau