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. 2022 Jul 29;49(13):4503–4515. doi: 10.1007/s00259-022-05901-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Collage of exemplary reconstructions from model M3 within the following order (left to right): Input (A), target (B), prediction (C), and difference map (D). The difference map is based on the subtraction of the original FullTime-PET with the AI-ExtremePET. Red spots indicate that the reconstructed intensity was lower than in the FullTime-PET, and blue spots indicate that the reconstructed intensity was higher than in the AI-ExtremePET