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. 2022 Aug 1;19(5):1514–1525. doi: 10.1007/s13311-022-01276-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Effects of intervention on cortical thickness among AAL regions (analysis with a false discovery rate threshold of p < 0.05 to control for multiple comparisons) in the FMI group in comparison to the HMI group. Compared with the HMI, the FMI group yielded significantly more beneficial effects on the cortical thickness of right medial superior frontal gyrus (p = 0.045), right temporal pole of superior temporal gyrus (p = 0.045) and middle temporal gyrus (p = 0.045) among the AAL regions. FMI facility-based multidomain intervention, HMI home-based multidomain intervention