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. 2022 Oct 13;13:1016927. doi: 10.3389/fimmu.2022.1016927

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Copyright © 2022 Raptis, Berger, Ciurea, Andrey, Polysopoulos, Lescuyer, Maletic, Riek, Scherer, von Loga, Safford, Lauper, Möller, Vuilleumier, Finckh and Rubbert-Roth

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Age-dependent odds of higher antibody levels following mRNA-1273 vs BNT162b2 vaccination at the different timepoints. The dashed red line indicates the location of odds ratio = 1, and the light blue-shaded areas the pointwise 95% confidence intervals. The grey arrows demonstrate, at the different timepoints, the increased benefit (in terms of higher odds of higher antibody levels) from vaccination with mRNA-1273 vs BNT162b2 for an IRD patient of 62 y vs 44 y (an interval coinciding with the study population age IQR).