TABLE 2.
Star allele | Allele frequency (N = 202) | Number of haplotypes observed (N = 404) | Activity Score a | Impact |
---|---|---|---|---|
*1 | 0.468 | 189 | 1 | Normal function |
*2 | 0.141 | 57 | 1 | Normal function |
*4 | 0.017 | 7 | 0 | No function |
*5 | 0.012 | 5 | 0 | No function |
*10 | 0.183 | 74 | 0.25 | Decreased function |
*35 | 0.007 | 3 | 1 | Normal function |
*41 | 0.067 | 27 | 0.5 | Decreased function |
*43 | 0.002 | 1 | ? | Uncertain function |
*71 | 0.089 | 36 | ? | Uncertain function |
*167 | 0.002 | 1 | ? | Unknown function |
*168 | 0.002 | 1 | ? | Unknown function |
*169 | 0.005 | 2 | ? | Unknown function |
*170 | 0.002 | 1 | ? | Unknown function |
Activity score and associated metaboliser phenotype as defined by Caudle et al. (2020).