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. 2022 Oct 26;12:17979. doi: 10.1038/s41598-022-22341-7

Table 2.

Summary of the applied therapies as reported in each eligible article.

Study Intervention group Dose Regime Duration (days) Control group Dose Regime Duration (days)
Wang et al. (2013)27 Ulinastatin + somatostatin 100000 U q12h 10 Somatostatin 250 mcg/h Continuous 10
Tu et al. (2014)28 Ulinastatin + octreotide 200000 U qd 14 Octreotide 0.5 g/(kg x h) N/A 14
Guo et al. (2015)13 Ulinastatin + octreotide

(1) 100000 U

(2) 50000 U

(1) q12h

(2) q12h

(1) for 3

(2) then 7–14

Octreotide 0.1 mg q8h 7–14
Wang et al. (2016)14 Ulinastatin + somatostatin 100000 U q12h 10 Somatostatin 3 mg Continuous 10
Wang et al. (2017)30 Ulinastatin + somatostatin 100000U

(1) q12h

(2) q24h

(1) for 3

(2) then 7

Somatostatin 6 mg Continuous 10
Yang et al. (2017)32 Ulinastatin + octreotide 100000 U q12h 10 Octreotide 0.1 mg q6h 7
Yang et al. (2018)15 Ulinastatin + octreotide 200000 U qd 14 Octreotide 0.1 mg bolus + 25 mcg/h Continuous 14
Meng et al. (2019)31 Ulinastatin + octreotide 100000U q12h 7 Octreotide 0.6 mg Continuous 7
Xu et al. (2019)29 Ulinastatin + somatostatin 100000 U q24h 7 Somatostatin 6 mg Continuous 7

U, unit; q, every; h, hour; d, day; mcg, microgram; mg, milligram, N/A, not reported.