Table 2.
Study | Intervention group | Dose | Regime | Duration (days) | Control group | Dose | Regime | Duration (days) |
---|---|---|---|---|---|---|---|---|
Wang et al. (2013)27 | Ulinastatin + somatostatin | 100000 U | q12h | 10 | Somatostatin | 250 mcg/h | Continuous | 10 |
Tu et al. (2014)28 | Ulinastatin + octreotide | 200000 U | qd | 14 | Octreotide | 0.5 g/(kg x h) | N/A | 14 |
Guo et al. (2015)13 | Ulinastatin + octreotide |
(1) 100000 U (2) 50000 U |
(1) q12h (2) q12h |
(1) for 3 (2) then 7–14 |
Octreotide | 0.1 mg | q8h | 7–14 |
Wang et al. (2016)14 | Ulinastatin + somatostatin | 100000 U | q12h | 10 | Somatostatin | 3 mg | Continuous | 10 |
Wang et al. (2017)30 | Ulinastatin + somatostatin | 100000U |
(1) q12h (2) q24h |
(1) for 3 (2) then 7 |
Somatostatin | 6 mg | Continuous | 10 |
Yang et al. (2017)32 | Ulinastatin + octreotide | 100000 U | q12h | 10 | Octreotide | 0.1 mg | q6h | 7 |
Yang et al. (2018)15 | Ulinastatin + octreotide | 200000 U | qd | 14 | Octreotide | 0.1 mg bolus + 25 mcg/h | Continuous | 14 |
Meng et al. (2019)31 | Ulinastatin + octreotide | 100000U | q12h | 7 | Octreotide | 0.6 mg | Continuous | 7 |
Xu et al. (2019)29 | Ulinastatin + somatostatin | 100000 U | q24h | 7 | Somatostatin | 6 mg | Continuous | 7 |
U, unit; q, every; h, hour; d, day; mcg, microgram; mg, milligram, N/A, not reported.