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. 2022 Sep 22;109(10):1761–1776. doi: 10.1016/j.ajhg.2022.08.013

Figure 6.

Figure 6

Manhattan plots from KnockoffTrio analysis for the Simons Foundation Powering Autism Research (SPARK)

The Manhattan plots of the W statistics from KnockoffTrio, the p values from the conventional association tests with the Bonferroni correction for controlling the FWER, and the q values from the BH procedure for controlling the FDR. The FDR target level for KnockoffTrio and the BH procedure is 0.1 or 0.2. Each locus is annotated with the closest gene name.