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. 2022 Sep 12;93(11):1154–1161. doi: 10.1136/jnnp-2022-329169

Table 3.

Excess death rate (EDR) with 95% CIs by decade after disease onset in deceased persons with multiple sclerosis, in Hordaland and Møre and Romsdal counties, Western Norway

Decade after disease onset
First Second Third Fourth Fifth
Women 0.3 (–0.17–0.71) 3.6 (3.01–4.12) 13.0 (12.11–13.81) 16.3 (14.29–17.96) 23.8 (19.12–27.46)
RRMS* 0.2 (–0.36–0.56) 3.0 (2.41–3.51) 11.0 (9.98–11.76) 12.5 (10.26–14.35) 21.4 (16.30–25.33)
PPMS† 1.8 (–0.71–3.14) 8.7 (5.73–10.74) 30.1 (26.64–32.57) 48.5 (42.73–52.51) 45.2 (29.92–53.64)
Men 0.5 (–0.59–1.24) 5.9 (4.70–6.90) 16.1 (14.24–17.68) 24.9 (21.09–28.01) 23.2 (11.53–31.99)
RRMS‡ 0.1 (–1.01–0.91) 4.2 (2.87–5.13) 14.3 (12.37–15.84) 18.8 (14.58–22.11) 24.0 (11.90–32.91)
PPMS§ 2.0 (–1.57–4.06) 13.9 (9.95–16.79) 24.8 (18.28–29.48) 62.7 (50.73–70.96) 17.3 (-39.98–43.02)
Total 0.4 (–0.09–0.77) 4.4 (3.88–4.93) 14.1 (13.26–14.88) 19.2 (17.39–20.74) 23.6 (18.97–27.46)

*n=412.

†n=115.

‡n=303.

§n=122.

PPMS, Primary progressive multiple sclerosis.; RRMS, Relapsing-remitting multiple sclerosis.