Table 3.
Decade after disease onset | |||||
First | Second | Third | Fourth | Fifth | |
Women | 0.3 (–0.17–0.71) | 3.6 (3.01–4.12) | 13.0 (12.11–13.81) | 16.3 (14.29–17.96) | 23.8 (19.12–27.46) |
RRMS* | 0.2 (–0.36–0.56) | 3.0 (2.41–3.51) | 11.0 (9.98–11.76) | 12.5 (10.26–14.35) | 21.4 (16.30–25.33) |
PPMS† | 1.8 (–0.71–3.14) | 8.7 (5.73–10.74) | 30.1 (26.64–32.57) | 48.5 (42.73–52.51) | 45.2 (29.92–53.64) |
Men | 0.5 (–0.59–1.24) | 5.9 (4.70–6.90) | 16.1 (14.24–17.68) | 24.9 (21.09–28.01) | 23.2 (11.53–31.99) |
RRMS‡ | 0.1 (–1.01–0.91) | 4.2 (2.87–5.13) | 14.3 (12.37–15.84) | 18.8 (14.58–22.11) | 24.0 (11.90–32.91) |
PPMS§ | 2.0 (–1.57–4.06) | 13.9 (9.95–16.79) | 24.8 (18.28–29.48) | 62.7 (50.73–70.96) | 17.3 (-39.98–43.02) |
Total | 0.4 (–0.09–0.77) | 4.4 (3.88–4.93) | 14.1 (13.26–14.88) | 19.2 (17.39–20.74) | 23.6 (18.97–27.46) |
*n=412.
†n=115.
‡n=303.
§n=122.
PPMS, Primary progressive multiple sclerosis.; RRMS, Relapsing-remitting multiple sclerosis.