Table 3.
Change in spirometry (completed to ATS standard) over the 3-year post-TB-treatment completion
| Variable | TB-treatment completion N=285 |
1-year post-TB treatment completion N=292 | 2-year post-TB treatment completion N=293 | 3-year post TB-treatment completion N=272 |
Mean change over 3 years (normalised to time) | P value comparing TB-treatment completion and 3-year visit |
| Spirometry* | ||||||
| FVC z-Score, mean (SD) | −0.91 (1.21) | −0.61 (1.11) | −0.55 (1.10) | −0.64 (1.10) | 0.28 (0.63) | <0.0001 |
| FEV1 z-score, mean (SD) | −1.07 (1.24) | −0.87 (1.18) | −0.81 (1.15) | −0.91 (1.16) | 0.16 (0.59) | <0.0001 |
| FEV1/FVC ratio z-score, mean (SD) | −0.38 (1.26) | −0.52 (1.30) | −0.56 (1.34) | −0.56 (1.30) | −0.19 (0.69) | <0.0001 |
| Reversible† | 4 (1.25%) | 7 (2.40%) | 4 (1.37%) | 1 (0.37%) | 0.1800 |
*ATS standard spirometry n=285/319 at TB-treatment completion=292/319 at 1-year visit n=293/319 at 2-year visit, n=272/301 at the 3-year last visit.
†Reversible spirometry with an FEV1 change of 12%.
FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity.