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. 2022 Jun 16;107(11):988–994. doi: 10.1136/archdischild-2022-324047

Table 1.

Gram-negative species as percentages of all infant bacteraemia (Gram-negative and Gram-positive) in high-income and low-income/middle-income countries*

High-income countries (n=55 studies) Low-income/middle-income countries (n=90 studies)
Isolates, n Proportion (95% CI) Isolates, n Proportion (95% CI)
Escherichia coli 5026 11.7% (9.40 to 14.4%) 2758 7.67% (6.36 to 9.24%)
Klebsiella spp 2401 3.17% (2.07 to 4.84%) 5915 19.0% (16.3 to 22.1%)
Pseudomonas spp 665 0.70% (0.04 to 1.09%) 1127 2.53% (1.83 to 3.49%)
Enterobacter spp 1395 0.63% (0.31 to 1.29%) 918 1.18% (0.74 to 1.85%)
Serratia spp 441 0.15% (0.06 to 0.37%) 237 0.02% (0.00 to 0.09%)
Proteus spp 34 0.01% (0.00 to 0.05%) 134 0.04% (0.01 to 0.13%)
Salmonella spp 61 0.00% (0.00 to 0.26%) 215 0.00% (0.00 to 0.03%)
Citrobacter spp 74 0.01% (0.00 to 0.06%) 249 0.09% (0.04 to 0.23%)
Haemophilus spp 272 0.02% (0.01 to 0.10%) 38 0.00% (0.00 to 0.06%)
Neisseria spp 19 0.00% (0.00 to 0.07%) 13 0.00% (0.00 to 0.20%)
Acinetobacter spp 394 0.14% (0.05 to 0.39%) 1996 3.25% (2.41 to 4.37%)
Moraxella spp 3 0.00% (0.00 to 3.05%) 10 0.00% (0.00 to 3.11%)
Other species or unspecified Gram-negative 868 0.42% (0.21 to 0.85%) 978 0.43% (0.22 to 0.83%)

*Estimates obtained by random-effects meta-analysis; see online supplemental file 4 for heterogeneity statistics.