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. 2022 Oct 13;13:985911. doi: 10.3389/fimmu.2022.985911

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Copyright © 2022 Chen, Yuan, Liu, Xia, Shi, Su, Wang, Li and Shang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ECM-APP-based analysis of tumor immune microenvironment. (A–C) The heat maps showed discrepancies in infiltration levels of immune cells across low- and high-risk subgroups premised on the train, test1, and test2 cohorts. The box plots showed discrepancies in ssGSEA scores between two risk subgroups in the (D, G) train cohort, (E, H) test1, and (F, I) test2cohorts. (J–L) The box plots showed discrepancies in immune checkpoint expression in low- and high-risk subgroups premised on the train, test1, and test2 cohorts. (* indicates p <0.05; ** indicates p < 0.01; *** indicates p < 0.001. ns, non-significant).