TABLE 3.
Association of baseline characteristics with PFS.
| Characteristics | Kaplan-meier survival analysis with log-rank test | Univariate cox regression analysis | Multivariate cox regression analysis | |||
|---|---|---|---|---|---|---|
| PFS (95%CI) | p-value | HR (95%CI) | p-value | HR (95%CI) | p-value | |
| Gender (female vs. male) | 3.85 (3.1–4.6) | 0.446 | 1.27 (0.68–2.38) | 0.449 | — | — |
| Age (<50 years vs. ≥ 50 years) | 3.85 (3.1–4.6) | 0.949 | 0.97 (0.43–2.21) | 0.950 | — | — |
| Comorbid conditions (yes vs. no) | 3.68 (2.5–4.9) | 0.844 | 1.09 (0.46–2.58) | 0.845 | — | — |
| Tumor sidedness (left-sided vs. right-sided) | 3.68 (2.7–4.7) | 0.772 | 1.13 (0.49–2.61) | 0.775 | — | — |
| Lymph node involvement (N2 vs. N0/N1) | 3.88 (2.8–4.97) | 0.858 | 0.94 (0.48–1.85) | 0.858 | — | — |
| Number of metastatic organ locations (<3 vs. ≥3) | 3.85 (3.1–4.6) | 0.759 | 1.1 (0.6–2.1) | 0.760 | — | — |
| Number of FTD/TPI administrations (≤5 vs. >5) | 3.85 (3.1–4.6) | <0.0001 | 0.18 (0.07–0.51) | 0.001 | 0.21 (0.07–0.59) | 0.003 |
| Surgery (no vs. yes) | 3.85 (3.1–4.6) | <0.0001 | 0.26 (0.12–0.58) | 0.001 | 0.34 (0.15–0.76) | 0.008 |