Table 2.
Relation between FXYD2 expression and immune landscape in ccRCC based on ssGSEA and ESTIMATE in TCGA, GSE40435, GSE57357, and E-MTAB-3267 cohort.
| Algorithm | Terms | TCGA | GSE40435 | GSE57357 | E-MTAB-3267 | ||||
|---|---|---|---|---|---|---|---|---|---|
| Cor | P value | Cor | P value | Cor | P value | Cor | P value | ||
| ssGSEA | Checkpoint | − 0.344 | <0.0001 | − 0.47 | <0.0001 | − 0.537 | <0.0001 | − 0.303 | 0.0197 |
| CCR | − 0.407 | <0.0001 | − 0.442 | <0.0001 | − 0.558 | <0.0001 | − 0.329 | 0.011 | |
| APC co-inhibition | − 0.219 | <0.0001 | − 0.464 | <0.0001 | − 0.299 | 0.011 | − 0.439 | 0.0005 | |
| ESTIMATE | Tumor purity | 0.392 | <0.0001 | 0.447 | <0.0001 | 0.292 | 0.0129 | 0.423 | 0.0008 |
| Immune score | − 0.295 | <0.0001 | − 0.411 | <0.0001 | − 0.231 | 0.0512 | − 0.342 | 0.008 | |
| Stromal score | − 0.489 | <0.0001 | − 0.393 | <0.0001 | − 0.28 | 0.0173 | − 0.477 | 0.0001 | |