Table 2.
Short-chain fatty acid response to bariatric surgery in all participants. Significance denoted with unadjusted p-value < 0.05 (bolded). Represents paired t-test.
| Pre-Surgery | Post-Surgery | Pre- vs. Post-Surgery | |
|---|---|---|---|
| Mean ± SD | Mean ± SD | p-Value | |
| Raw values (mmol/kg fecal weight) | |||
| Total SCFA | 23.1 ± 12.1 | 17.2 ± 6.6 | 0.026 |
| Acetate | 14.1 ± 7.9 | 10.9 ± 4.9 | 0.037 |
| Propionate | 3.5 ± 1.9 | 2.3 ± 1.3 | 0.018 |
| Butyrate | 3.1 ± 1.7 | 2.1 ± 1.1 | 0.023 |
| Valerate | 0.8 ± 0.5 | 0.5 ± 0.2 | 0.032 |
| Isobutyrate | 0.8 ± 0.5 | 0.7 ± 0.3 | 0.567 |
| Isovalerate | 0.6 ± 0.4 | 0.5 ± 0.2 | 0.127 |
| Straight SCFA | 21.5 ± 11.4 | 15.8 ± 6.2 | 0.019 |
| Branched SCFA | 1.5 ± 0.9 | 1.4 ± 0.6 | 0.567 |
| Proportions (%) | |||
| Acetate | 61.0 ± 6.0 | 63.0 ± 9.0 | 0.403 |
| Propionate | 15.0 ± 3.0 | 13.0 ± 4.0 | 0.072 |
| Butyrate | 13.0 ± 3.0 | 12.0 ± 5.0 | 0.233 |
| Valerate | 4.0 ± 3.0 | 3.0 ± 1.0 | 0.446 |
| Isobutyrate | 3.0 ± 1.0 | 4.0 ± 1.0 | 0.026 |
| Isovalerate | 3.0 ± 1.0 | 3.0 ± 1.0 | 0.616 |
| Straight SCFA | 93.0 ± 2.0 | 92.0 ± 1.0 | 0.026 |
| Branched SCFA | 7.0 ± 2.0 | 8.0 ± 3.0 | 0.026 |