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. 2022 Oct 19;12(10):1012. doi: 10.3390/membranes12101012

Table 1.

Parameters derived from WT and mutant GlyR expressed in oocytes.

	Gly			Tau
	pEC₅₀, M	EC₅₀ μM	n_H	pEC₅₀, M	EC₅₀ μM	n_H	% I_maxTau /I_maxGly	n
WT	4.282 ± 0.05	52	2.3 ± 0.5	3.235 ± 0.05	583	1.7 ± 0.3	50 ± 4	5
P96A	3.518 ± 0.03 *	304	2.2 ± 0.3	2.612 ± 0.03 *	2440	1.9 ± 0.2	36 ± 2 *	5
P146A	3.932 ± 0.05 *	117	2.4 ± 0.7	2.850 ± 0.06 *	1410	1.5 ± 0.3	39 ± 3 *	5
P230A	3.579 ± 0.03 *	264	2.2 ± 0.4	2.925 ± 0.03 *	1190	2.2 ± 0.4	20 ± 1 *	5

pEC₅₀ = −log EC₅₀; n_H = Hill coefficient. Data = mean ± SEM, n = 5. * = significantly different to WT, p < 0.05.