Figure 5.

KHF4 and KHF5 replication in lung tissue. (A) Lungs were collected from KHFV-infected mice at 5 dpi and cultured. After 7 days, the supernatant was collected for real-time RT-PCR. (B) Uninfected BALB/c mouse lungs were collected and cultured as described above. After infection with KHFV, the supernatant was collected at 7 dpi for real-time RT-PCR analysis. (C) Viral N protein in the lung tissue as shown in Figure 5B detected by Western blot. Results from mock inoculated mouse and lung tissue are shown in NC (Significance was assigned as * p < 0.05, and *** p < 0.001).