Table 3.
Cross-reactivity among the four JE serocomplex viruses, JEV, MVEV, WNV and USUV, and the outcomes for disease are depicted. Viruses listed across represent preexisting immunity, primary challenge or vaccination and viruses down the column represent secondary infection. Flaviviruses circulating in distinct areas with no currently reported co-existence are denoted by ‘Distinct geography’.
| Virus (Infection or Vaccination) | Outcome | JEV | MVEV | WNV | USUV |
|---|---|---|---|---|---|
| JEV | Protection Pathology |
[203] [195] - |
[216] [186] [217] [218] [186] |
[203] [217] [219] [220] |
Distinct geography |
| MVEV | Protection Pathology |
[221] [217] [195] [186] |
[216] [204] - |
TBD/Unknown TBD/Unknown |
Distinct geography |
| WNV | Protection Pathology/no protection |
[222] [223] [195] [224] [217] [219] [225] [226] |
TBD/Unknown - |
[227] [228] - |
[229] [230] [231] - |
| USUV | Protection Pathology |
Distinct geography TBD/Unknown |
Distinct geography TBD/Unknown |
[227] [232] TBD/Unknown |
[233] [234] - |