Table 2.

Univariable and multivariable logistic regression analysis on risk factors for allergic reactions following COVID-19 vaccinations. Odds ratios unadjusted (ORs) and adjusted (aORs) with 95% confidence intervals (95% CI).

FACTORS			UNIVARIABLE		MULTIVARIABLE
			OR (95% CI)	p-Value	aOR (95% CI)	p-Value
Age (years, linear term)			0.99 (0.97; 1.01)	0.286
Sex	Males		reference		reference
	Females		2.74 (1.14; 6.54)	0.023	3.05 (1.22; 7.65)	0.017
Atopic dermatitis	No		reference
	Yes		1.34 (0.38; 4.73)	0.653
Inhalant allergy	No		reference
	Yes		1.31 (0.72; 2.39)	0.375
Food allergy	No		reference
	Yes		0.91 (0.47;1.76)	0.771
Drug allergy	No		reference		reference
	Yes		0.33 (0.18; 0.62)	0.001	0.30 (0.15; 0.58)	<0.001
Venom allergy	No		reference
	Yes		1.34 (0.38; 4.74)	0.653
Latex allergy	No		reference		reference
	Yes		2.25 (1.00; 5.07)	0.050	1.81 (0.77; 4.24)	0.172
Contrast medium allergy	No		reference
	Yes		0.75 (0.23; 2.42)	0.633
Asthma	No		reference
	Yes	Controlled	1.15 (0.10; 12.9)	0.910
		Uncontrolled	0.98 (0.46; 2.01)	0.910
Chronic urticaria	No		reference
	Yes		0.19 (0.02; 1.56)	0.123
Angioedema	No		reference
	Yes		0.76 (0.20; 2.89)	0.682
Number of allergic reactions (linear term)			0.91 (0.68; 1.22)	0.534
Vaccine type	Comirnaty		reference
	Spikevax		0.96 (0.39; 2.31)	0.957
	Vaxzevria		1.83 (0.29; 11.4)	0.855