Table 3.
The most common features of primary CNS vasculitides and their differences.
| PACNS | CAARI | ABRA | |
|---|---|---|---|
| Cognitive decline | 50–70% [17] | 48–76% [25,28] | 71% [29] |
| Focal neurological symptoms | 25–30% [17] | 46% [25,28] | 51% [29] |
| Severe headache | 50–60% [17] | 32–41% [25,28] | 35% [29] |
| Seizures | 25–30% [17] | 31% [25,28] | 30% [29] |
| Elevated ESR or CRP [31] | Uncommon | Up to 30% | |
| Elevated CSF protein [31] | 80–90% | 71% | |
| CSF pleocytosis [31] | 80–90% | 44% | |
| Intracranial hemorrhage [31] | 8% | 20% | 14% |
| Meningeal gadolinium enhancement [31] | 12% | 56% | 57% |
PACNS—primary angiitis of the central nervous system, CAARI—cerebral amyloid angiopathy related inflammation, ABRA—amyloid β-related angiitis, ESR—erythrocyte sedimentation rate, CRP– C-reactive protein, CSF—cerebrospinal fluid.