Table 1.
Compounds | IC50 | EC50 | Targets | References |
---|---|---|---|---|
1 | - | - | Entry inhibitors | [16] |
8 | 57.7 μM 30.3 μM |
- | Protease inhibitors Integrase inhibitors |
[46] [45] |
10 | 8 μM | - | Protease inhibitors | [28] |
35 μM | - | Integrase inhibitors | [45] | |
11 | 13 μM | - | Protease inhibitors | [28] |
13 | - | - | Protease inhibitors | [30] |
16 | 24.8 μM | - | Integrase inhibitors | [45] |
17 | 17.7 μM | - | Integrase inhibitors | [45] |
18 | 11.6 μM | - | Reverse transcriptase inhibitor | [36] |
19 | 0.03 μM | - | Maturation inhibitors | [44] |
20 | 0.02 μM | - | - | [44] |
21 | 4.08 μM | - | Replication inhibition | [52] |
22 | 4.18 μM | - | Replication inhibitors | [52] |
23 | 1.70 μM | - | Replication inhibitors | [52] |
34 | >1.0 mM | - | Protease inhibitors | [47] |
35 | 7.8 μg/mL | - | Protease inhibitors | [48] |
40 | 30 μM | - | Protease inhibitors | [48] |
41 | 48 μM | - | Protease inhibitors | [48] |
42 | 25 μM | - | Protease inhibitors | [48] |
43 | - | 20.69 μg/mL | - | [32] |
44 | - | 16.6 μg/mL | - | [32] |
45 | - | 16.2 μg/mL | - | [32] |
46 | - | 10.3 μg/mL | - | [32] |
15.79 μM | - | Protease inhibitors | [35] | |
47 | 20.44 μM | - | Protease inhibitors | [35] |
48 | - | 6.1 μg/mL | - | [33] |
50 | - | 1.4 μg/mL | - | [34] |
53 | - | 1.24 μM | - | [53] |
54 | - | - | - | [54] |