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. 2022 Sep 21;15(10):1169. doi: 10.3390/ph15101169

Table 3.

Summary of anti-CoV triterpenoids and their targets and activities.

Compounds IC50 Targets Virus References
1 Inhibits SARS-CoV replication, adsorption, and penetration; SARS-CoV [68]
Protease inhibitor SARS-CoV-2 [73]
7 - SARS-CoV-2 [74]
8 3CL hydrolase inhibitor SARS-CoV-2 [75]
10 12.57 SARS-CoV-2 Mpro inhibitor SARS-CoV-2 [76]
16 14.55 SARS-CoV-2 Mpro inhibitor SARS-CoV-2 [76]
17 89.67 SARS-CoV-2 Mpro inhibitor SARS-CoV-2 [76]
51 3.22 SARS-CoV-2 Mpro inhibitor SARS-CoV-2 [76]
52 4.12 Inhibits SARS-CoV replication and adsorption SARS-CoV [77]
6.25 - MERS-CoV [77]