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. 2022 Oct 26;611(7935):352–357. doi: 10.1038/s41586-022-05371-z

Table 1.

Public antibody properties are consistent with recombination biology

Data source Recurrences Average junction property
All cells (mean ± s.e.m.) VDDJ cells (mean ± s.e.m.) Insertion length (nt) Substitution rate in junctions from VDDJ rate CDRH3 length (amino acids)
All cells Cells with no insertions
Real 754.0 0.0 5.0 15.6% 7.2% 0.52% 18.4
Simulated 1,189.6 ± 10.8 1.8 ± 0.7 5.3 16.5% 7.3% 0.32% 18.1

Junction properties of observed and simulated antibody sequences in this study, using ten simulation replicates (see also Fig. 3 and details of simulations in Methods). nt, nucleotides.