Extended Data Table 2.

Flow categories by donor with number of cells and naive fraction

Total numbers of cells captured via fluorescence-activated flow cytometry with exactly two chains are shown, along with the fraction of naive sequences, as determined computationally by lack of exhibited SHM. Cells were sorted for naive, unswitched, switched and plasmablast, and in some libraries, sort categories were combined. Entries are blank if no data were generated. The table only accounts for cells that exhibited exactly one heavy and one light chain, and which were determined to lie in a valid clonotype having exactly two chains.