Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 26;611(7934):155–160. doi: 10.1038/s41586-022-05368-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — Tumour tissue samples harvested from patients at baseline, and post relatlimab and nivolumab treatment were analysed in a single experiment by CyTOF (a–c). a, Frequency of CD45⁺ cells was assessed through manual gating. b, Frequency of an effector CD8⁺ T cell subset (CD3⁺CD8⁺CD45RO^low) in unsupervised clustering is shown. c, Frequency of a memory CD4⁺ subset (CD45RO⁺ICOS⁺ TCF7⁺BTLA⁺CD28⁺TIGIT⁺) was determined by unsupervised clustering. Data shown in a–c are mean ± s.d., and n values are indicated in the figure. P values shown in each graph were calculated by two-tailed unpaired t-test, with no multiple comparisons. Red indicates pathologic responders; blue, non-responders. CyTOF, mass cytometry; NR, non-responder; R, responder; wk, week.

Source data.