Figure 4. Primary Outcome, Secondary Outcomes, and Subgroup Analyses for the Comparison of Selective Decontamination of the Digestive Tract (SDD) vs Standard Care.

Subgroup and secondary outcomes are presented based on calculations using vague priors. Full details of the priors are presented in eAppendix 1 in the Supplement. ICU indicates intensive care unit.

^aConfidence interval.

^bTotal number of trials is 31 because the de Smet et al²⁷ study contributes both intravenous (IV) and non-IV data. Participant numbers for the control group have been split evenly between the IV and non-IV groups so they remain the same as the main publication (ie, not double counted).

^cNo data in medical ICUs.

^dThe effect size is the log of the risk ratio. The exponent of the values provides the estimated risk ratio, also shown in eFigure 17 in the Supplement.

^eMedian duration of ventilation was 11.8 days (IQR, 8.7-15.1) in the SDD group and 12.5 days (IQR, 8.7-18.0) in the control group.

^fMedian intensive care unit length of stay was 17.2 days (IQR, 12.2-22.0) in the SDD group and 18.9 days (IQR, 12.6-27.0) in the control group.

^gMedian hospital length of stay was 27 days (IQR, 26.3-30.0) in the SDD group and 29 days (IQR, 27-31) in the control group.