Table 5.
Differences in baseline characteristics of low dose and standard dose using the propensity score-matching sample
| Low-dose (n = 88) | Standard-dose (n = 88) | p-value | |
|---|---|---|---|
| Female, (n, %) | 36 (40.9%) | 26 (29.5%) | 0.115 |
| Age, (median, IQR),y | 68 (60-78) | 67 (61-72) | 0.151 |
| Hypertension, (n, %) | 54 (61.4%) | 67 (73.9%) | 0.076 |
| Hyperlipidemia, (n, %) | 34 (38.6%) | 42 (47.7%) | 0.223 |
| Diabetes, (n, %) | 19 (21.6%) | 23 (26.1%) | 0.479 |
| Chronic heart failure, (n, %) | 14 (15.9%) | 18 (20.5%) | 0.434 |
| Atrial fibrillation (n, %) | 29 (33.0%) | 33 (37.5%) | 0.528 |
| Previous ischemic stroke (n, %) | 14 (15.9%) | 8 (9.1%) | 0.171 |
| Baseline NIHSS score (median, IQR) | 7 (4-12) | 7 (4-12) | 0.732 |
| Hyperdense MCA sign (n, %)* | 10 (11.4%) | 6 (6.8%) | 0.294 |
| Type of occluded vessel (n, %) | 0.640 | ||
| Anterior | 78 (84.1%) | 71 (80.7%) | |
| Posterior | 5 (5.7%) | 4 (4.3%) | |
| Mixed | 6 (6.8%) | 11 (12.5%) | |
| Baseline SBP (mmHg) (median, IQR) | 155 (132-165) | 151 (136-167) | 0.696 |
| Baseline blood glucose (mmol/L) | 6.7 (6.0-8.1) | 7.0 (6.1-8.6) | 0.352 |
| Baseline blood glucose ≥ 10mmol/L (n, %) | 14 (15.9%) | 17 (54.8%) | 0.553 |
| Discharge NIHSS | 2 (1-5) | 2 (1-7) | 0.732 |
| Discharge mRS 0-3 (n, %) | 61 (69.3%) | 56 (63.6%) | 0.425 |
| sICH (n, %) | 2 (2.3%) | 10 (11.4%) | 0.032 |
| Any ICH (n, %) | 14 (15.9%) | 18 (20.5%) | 0.434 |
| Inhospital Mortality (n, %) | 0 (0.0%) | 3 (3.3) | 0.246 |
Abbreviations: MCA, middle cerebral artery; NIHSS, national institute of health stroke scale; SBP, systolic blood pressure; sICH, symptomatic intracerebral hemorrhage;
* Data available in 160 patients.