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In vitro release kinetics of BZN and TIB from the optimized (F9) formulation.
| Model | BZN Release | TIB Release | ||||
|---|---|---|---|---|---|---|
| k | r2 | n | k | r2 | n | |
| Zero order | 30.059 | 0.7499 | - | 28.610 | 0.8829 | - |
| First order | 0.795 | 0.9797 | - | 0.616 | 0.9444 | - |
| Higuchi model | 52.41 | 0.9514 | - | 48.464 | 0.9137 | - |
| Korsmeyer–Peppas model | 51.13 | 0.9524 | 0.528 | 37.74 | 0.9189 | 1.02 |
| Hixson–Crowell model | 0.224 | 0.9941 | - | 0.175 | 0.9696 | - |
