Table III.
Human placental proteins identified by liquid chromatography electrospray ionization tandem mass spectrometry from the group of fetal growth restriction cases.
Accessiona | Identified proteinb | Scorec | Molecular mass (Da)d | Matched Peptidese | Sequence coverage (%)f | Exponentially Modified Protein Abundance Indexg |
---|---|---|---|---|---|---|
P02647 | Apolipoprotein A-I OS=Homo sapiens OX=9606 GN=APOA1 PE=1 SV=1 | 486 | 30,759 | 14 | 33.3 | 3.48 |
P32119 | Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 | 300 | 22,016 | 7 | 25.8 | 2.12 |
P63104 | 14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 | 237 | 27,866 | 7 | 25.3 | 1.86 |
P01009 | Alpha-1-antitrypsin OS=Homo sapiens OX=9606 GN=SERPINA1 PE=1 SV=3 | 497 | 46,845 | 12 | 23.9 | 1.46 |
P60174 | Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=3 | 363 | 31,002 | 9 | 20.6 | 1.25 |
P07195 | L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 | 244 | 36,845 | 5 | 15.3 | 0.77 |
P04040 | Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 | 468 | 59,903 | 10 | 16.9 | 0.76 |
P02790 | Hemopexin OS=Homo sapiens OX=9606 GN=HPX PE=1 SV=2 | 354 | 52,241 | 15 | 11.3 | 0.76 |
P27797 | Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 | 401 | 48,250 | 9 | 20.4 | 0.69 |
P07237 | Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 | 316 | 57,403 | 7 | 16.9 | 0.67 |
P26038 | Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3 | 487 | 67,870 | 11 | 10.7 | 0.64 |
P14618 | Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 | 248 | 58,360 | 7 | 8.9 | 0.43 |
P29401 | Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 | 272 | 68,387 | 7 | 7.7 | 0.36 |
O43707 | Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 | 253 | 105,156 | 8 | 7.2 | 0.33 |
P00450 | Ceruloplasmin OS=Homo sapiens OX=9606 GN=CP PE=1 SV=1 | 344 | 122,817 | 7 | 6.7 | 0.19 |
Q9BVA1 | Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 | 238 | 50,289 | 4 | 7.2 | 0.18 |
Database accession numbers according to: Uniprot 2019_02 (559228 sequences; 200905869 residues) database with Homo sapiens (human) (20492 sequences) filter.
Identified homologous proteins.
Mascot Search Probability Based Mowse Score. Ions score is-10×Log(P), where P is the probability that the observed match is a random event. Protein scores >31 indicate identity or extensive homology (P<0.05).
Theoretical mass (Da) of identified proteins. The values were retrieved from the protein database.
Number of matched peptides with Mascot search data (www.matrixscience.com).
Amino acid sequence coverage for the identified proteins.
Exponentially modified protein abundance index of identified protein according to Mascot Search data.