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. Author manuscript; available in PMC: 2022 Oct 27.
Published in final edited form as: Head Neck. 2020 Sep 29;43(1):212–222. doi: 10.1002/hed.26479

Table 5.

Comparison of studies with rapid recurrence

Study Disease Site Number of patients Imaging consistent with rapid recurrence Biopsy confirmed rapid recurrence Modality Significant factors for rapid recurrence on MVA Local control of patients with rapid recurrence

Shitani et al. All head & neck + skin 91 29.7% (n=27) 41% (11 of 27) PET/CT 2 yr LRC 70%
Liao et al. Oral cavity 29 24% (n=7) - PET/CT 2 yr DFS 29%
Dutta et al. Oral cavity 44 31.8% (n=14) 21% (3 of 14) PET/CT 2 yr LC 77%
Hosni et al. Oral cavity 601 15% (n=88) 32% (22 of 88) CT or MRI Oral tongue,pT3–4, pN2–3, positive margin 3 yr LC 69% (70 Gy)
Current series All head & neck 194 21% (n=40) - CT Simulation ENE 2 yr LC 56% (>60Gy)