Table 5.
Study | Disease Site | Number of patients | Imaging consistent with rapid recurrence | Biopsy confirmed rapid recurrence | Modality | Significant factors for rapid recurrence on MVA | Local control of patients with rapid recurrence |
---|---|---|---|---|---|---|---|
| |||||||
Shitani et al. | All head & neck + skin | 91 | 29.7% (n=27) | 41% (11 of 27) | PET/CT | 2 yr LRC 70% | |
Liao et al. | Oral cavity | 29 | 24% (n=7) | - | PET/CT | 2 yr DFS 29% | |
Dutta et al. | Oral cavity | 44 | 31.8% (n=14) | 21% (3 of 14) | PET/CT | 2 yr LC 77% | |
Hosni et al. | Oral cavity | 601 | 15% (n=88) | 32% (22 of 88) | CT or MRI | Oral tongue,pT3–4, pN2–3, positive margin | 3 yr LC 69% (70 Gy) |
Current series | All head & neck | 194 | 21% (n=40) | - | CT Simulation | ENE | 2 yr LC 56% (>60Gy) |