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. 2022 Oct 14;27(20):6906. doi: 10.3390/molecules27206906

Table 7.

In vitro urease inhibitory activity of synthesized N′-benzylidene-4-(t-Bu)benzohydrazide derivatives (426).

Compounds IC50 ± SEM (µM) Compounds IC50 ± SEM (µM)
4 88.75 ± 7.71 16 79.01 ± 7.53
5 56.57 ± 3.18 17 27.45 ± 1.65
6 13.33 ± 0.58 18 66.14 ± 1.79
7 64.50 ± 3.97 19 67.48 ± 4.16
8 80.01 ± 7.43 20 51.41 ± 11.50
9 63.50 ± 3.97 21 71.27 ± 2.47
10 63.54 ± 3.97 22 38.57 ± 11.54
11 63.52 ± 2.97 23 251.74 ± 6.82
12 39.57 ± 11.54 24 37.47 ± 12.54
13 80.93 ± 7.43 25 13.42 ± 0.33
14 81.21 ± 7.4 26 49.47 ± 12.74
15 82.21 ± 7.43 Thiourea 21.14 ± 0.42

SEM is the standard error of the mean, thiourea = standard for urease inhibition activity.