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. 2022 Sep 28;15(10):1205. doi: 10.3390/ph15101205

Table 1.

Effect on blood glucose levels in diabetic rats by N. nucifera crude, nuciferine and norcoclaurine.

Sample Treatment Blood Glucose Level (mg/mL)
Days = 0 5 10 15
Normal control (Nc) 0.95 ± 1.65 0.93 ± 1.25 0.88 ± 0.12 0.85 ± 1.53
Diabetic control (Dc) 2.52 ± 2.85 2.31 ± 2.32 2.10 ± 1.68 2.00 ± 1.32
Dc+ glibencamide (10 mg/kg) 2.00 ± 1.85 1.54 ± 1.68 1.37 ± 1.20 0.94 ± 1.20 *
Dc+ crude (100 mg/kg) 2.10 ± 2.85 1.65 ± 1.08 1.44 ± 1.03 1.20 ± 1.90
Dc + crude (200 mg/kg) 2.15 ± 1.35 1.60 ± 1.55 1.52 ± 0.97 1.11 ± 1.79 *
Dc + nuciferine (10 mg/kg) 2.05 ± 3.85 1.64 ± 2.51 1.42 ± 1.23 1.00 ± 1.45 *
Dc + norcoclaurine (10 mg/kg) 2.10 ± 4.67 1.70 ± 3.25 1.58 ± 1.43 1.08 ± 3.15

Note: Each value is mean ± SEM of six animals; * p < 0.05.