Table 3.

Effect of N. nucifera crude, nuciferine and norcoclaurine on the TBARS and SOD, CAT, GPx and GSH enzymes activities in diabetic rats.

Parameter	TBARS (nmol MDA/mg Protein)	SOD SOD/mg Protein	CAT E/min/mg Protein	GPx nmol NADPH/min/mg Protein	GSH GSH/mg Protein
Normal control (Nc)	1.75 ± 0.5	7.31 ± 0.9	6.86 ± 3.8	8.12 ± 0.6	95.10 ± 5.04
Diabetic control (Dc)	3.10 ± 1.3 *	3.01 ± 0.3 *	2.91 ± 4.2 *	3.55 ± 0.9 **	45.30 ± 7.27 **
Dc + glibenclamide (10 mg/kg)	1.55 ± 0.8 *	5.91 ± 0.3 *	6.45 ± 3.9	7.80 ± 1.6 *	89.52 ± 4.74 *
Dc + crude (100 mg/kg)	2.65 ± 0.5	4.90 ± 0.2 *	2.32 ± 2.8 *	6.20 ± 2.8 *	67.15 ± 3.95
Dc +crude (200 mg/kg)	1.96 ± 0.7 *	5.20 ± 1.5 *	4.95 ± 3.5 *	7.10 ± 3.0 **	78.56 ± 4.19 **
Dc + nuciferine (10 mg/kg)	1.60 ± 0.8 *	7.1 ± 0.2 *	6.16 ± 0.7 *	7.98 ± 0.9 *	86.96 ± 0.7 *
Dc + norcoclaurine (10 mg/kg)	1.98 ± 0.9 *	6.2 ± 0.7 *	5.1 ± 0.3 *	6.70 ± 0.89 *	76.68 ± 0.4 *

Note: * p < 0.05: normal control vs. diabetic control; diabetic control vs. treated groups. ** p < 0.01.