Table A1.

Summary of the studies included in the review.

Reference	Country	Type of Article	Topic	Summary
Athar 2022 [26]	Iran	Editorial	Preventive measures in healthcare settings	The study is a mini-review of preventive practices for disease control in surgery rooms.
Atkinson 2022 [35]	UK	Case report	Risk of contagion in workplace	Environmental sampling was performed to identify MPXV contamination in an office where a worker infected with monkeypox had worked with evidence of low contamination.
Costello 2021 [19]	USA	Case report	Risk of contagion in healthcare settings	A total of 40 HCWs were identified as contacts. No HCW met the criteria for high-risk exposure, and no doses of the preventive smallpox vaccine were administered. Active surveillance and symptom monitoring were implemented. No disease transmission was detected.
Croft 2007 [33]	USA	Observational study	Risk of contagion in veterinarian settings	The study documented the occupational contagion of veterinary staff and other pet staff through contact with infected prairie dogs.
Dell 2020 [34]	Uganda	Cross-sectional study	Knowledge and attitudes of bushmeat traders toward monkeypox virus	Bushmeat trade workers were interviewed regarding their attitudes and practices toward zoonosis prevention. The majority believed that pathogens causing stomach ache or diarrhea (74.6%) and monkeypox (62.2%) can be transmitted by wildlife.
Doshi 2018 [29]	Congo	Case series	Preventive measures in healthcare settings	The study reported the response measures, including community education and surveillance strengthening, during a monkeypox outbreak in 2017 in the Republic of Congo.
Erez 2019 [22]	Israel	Case report	Risk of contagion in healthcare settings	A total of 11 HCWs were recognized as a monkeypox patient’s contacts; they were offered smallpox vaccination, but only 1 HCW agreed. All contacts were followed up on for 21 days; no virus transmission was detected.
Fleischauer 2005 [16]	USA	Cross-sectional study	Risk of contagion in healthcare settings	The study reported the exposure of HCWs to 3 cases of monkeypox, with at least 1 unprotected encounter. One asymptomatic HCW showed laboratory evidence of recent Orthopoxvirus infection, which was possibly attributable to either a recent infection or smallpox vaccination.
Harapan 2020a [32]	Indonesia	Cross-sectional study	Knowledge and attitudes of physicians toward monkeypox virus	Among 407 Indonesian doctors, 96% expressed acceptance of a free vaccination. Those 30 years old or younger had 2.94 times greater odds of vaccine acceptance compared to those who were older. The length of practice was also associated with the willingness of vaccination.
Harapan 2020b [30]	Indonesia	Cross-sectional study	Knowledge and attitudes of physicians toward monkeypox virus	In Indonesia, out of a total of 432 doctors, 10.0% and 36.5% of them had a good level of knowledge using an 80% and 70% cutoff point for the knowledge domain, respectively.
Hobson 2021 [21]	UK	Case report	Risk of contagion in healthcare settings	All contacts, including HCWs, identified for active surveillance completed the 21-day surveillance period from their last date of exposure and no transmissions outside the index family were identified.
Koenig 2022 [28]	USA	Editorial	Preventive measures in healthcare settings	A tool, 3I (identify, isolate, inform), was presented to manage patients with suspected and confirmed monkeypox.
Kyaw 2020 [20]	Singapore	Case report	Risk of contagion in healthcare settings and preventive measures after exposure	The level of exposure to a monkeypox patient was investigated through telephonic interviews and contact tracing. A total of 27 HCWs were identified to have had close contact, as defined by direct contact with the patient himself or the patient’s surroundings, contact with the patient’s linens, or contact with the patient’s specimens in the lab. All had protected exposure to the patient, with the appropriate and adequate use of PPE. None developed symptoms.
Lepellettier 2022 [25]	France	Review	Preventive measures in healthcare settings	Specific measures were provided for healthcare workers, including patient isolation and adequate PPE.
Nakoune 2017 [17]	Central African Republic	Case series	Risk of contagion in healthcare settings	Occupational monkeypox infections of nurses and transport clerks were reported during a familial outbreak of monkeypox in 2016 in the Central African Republic.
Nörz 2022 [23]	Germany	Observational study	Risk of contagion in healthcare settings	The study found a high viral load on several hospital surfaces that had been in contact with infected patients.
Ogoina 2019 [27]	Nigeria	Cross-sectional study	Preventive measures in healthcare settings	During the 2017 monkeypox outbreak, the hospital established a make-shift isolation ward for case management, constituted a monkeypox response team, and provided infection control resources. Training and education were major points of intervention.
Palmore 2022 [24]	USA	Editorial	Preventive measures in healthcare settings	The paper provided an overview of the fundamental preventive practices to be implemented in HCW settings.
Petersen 2019 [18]	Congo	Editorial	Risk of contagion in healthcare settings	The healthcare-associated transmission of monkeypox was observed on multiple occasions in areas where the disease is endemic, where vaccination for workers can be useful to reduce the occupational risk of disease.
Riccò 2022 [31]	Italy	Cross-sectional study	Knowledge and attitudes of physicians toward monkeypox virus	The knowledge status was quite unsatisfying, with substantial knowledge gaps on all aspects of MPX. An analysis of risk perception suggested a substantial overlooking of MPX as a pathogen.
Vaughan 2020 [15]	UK	Case report	Risk of contagion in healthcare settings	Reported the occupational contagion of a HCW from an infected patient, probably through contact with contaminated bedding.