Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 26;14(10):2044. doi: 10.3390/pharmaceutics14102044

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

NIL10 induces M2 macrophage polarization in the hearts of mice subjected to IR and induces the expression of resolving cytokines in mice and pigs. (A) Flow cytometry analysis of macrophage populations in mouse hearts after 3 and 7 days of IR. The percentage of the M2 CD68+/CD206+ population was selected from the necrotic and risk areas of the hearts. (n = 6 mice/group). Differences between groups were compared using one-way ANOVA. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. (B) Clustered heat map of the differentially expressed cytokines in mice. (C) Clustered heat map of the differentially expressed cytokines in pigs. Red arrows indicated anti-inflammatory cytokines.