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. 2022 Sep 26;14(10):2044. doi: 10.3390/pharmaceutics14102044

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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NIL10 induces phosphorylation of IL10RA and STAT3. (A) Immunoblot detection of P-IL10RA (upper), and total IL-10-RA in the healthy (H) and necrotic (N) areas of mouse hearts at day 7 after IR (p < 0.04 NIL10 vs. NIL10SC necrotic areas). (B) Immunoblot detection of P-STAT3, and total STAT3 in the same protein extracts. n = 6 mice/group. Results are expressed as Mean ± SD (p < 0.05 NIL10 vs. NIL10SC necrotic areas). (C) Immunoblot detection as described in A. of pig hearts at day 7 after IR (p < 0.05 NIL10 vs. NIL10SC necrotic areas). (D) Immunoblot detection of P-STAT3, and total STAT3 in the same protein extracts. n = 6 pigs/group. Results are expressed as Mean ± SD (* p < 0.005 NIL10 vs. NIL10SC necrotic areas).