Table 5:
Adult and pediatric EBV risk categories by organ type
| n (%) of transplants within organ type | |||||
|---|---|---|---|---|---|
| Age group and organ type | D–/R– | D+/R– | D–/R+ | D+/R+ | n |
| Adult | |||||
| Kidney* | 12 (0.7) | 91 (5.1) | 142 (8.0) | 1,539 (86.3) | 1,784 |
| Liver | 3 (0.3) | 20 (1.8) | 71 (6.4) | 1,018 (91.5) | 1,112 |
| Heart | 0 (0.0) | 31 (6.0) | 43 (8.3) | 442 (85.7) | 516 |
| Lung | 1 (0.2) | 35 (6.3) | 37 (6.7) | 480 (86.8) | 553 |
| Total | 16 (0.4) | 177 (4.5) | 293 (7.4) | 3,479 (87.7) | 3,965† |
| Pediatric | |||||
| Kidney* | 2 (2.5) | 27 (34.2) | 3 (3.8) | 47 (59.5) | 79 |
| Liver | 17 (8.2) | 106 (51.0) | 21 (10.1) | 64 (30.8) | 208 |
| Heart | 18 (12.7) | 64 (45.1) | 12 (8.5) | 48 (33.8) | 142 |
| Lung | 3 (37.5) | 0 (0.0) | 1 (12.5) | 4 (50.0) | 8 |
| Total | 40 (9.2) | 197 (45.1) | 37 (8.5) | 163 (37.3) | 437† |
Notes: Seropositive and indeterminate donors and recipients aged younger than 12 mo were included in this table and risk adjusted them to be D+ or R–, respectively, to account for the potential effects of passive maternal antibody. Indeterminate donors and recipients aged older than 12 mo were risk adjusted to be D+ or R–, respectively
*Organs were grouped as follows: kidney–pancreas with kidneys, small bowel and multivisceral with liver, and heart–lung with lung
†Exclusions due to missing serology in adults (n = 515) and pediatrics (n = 38). Missing EBV serology results were most common before implementation of routine screening in 1994, accounting for 90% of missing donor and 65% of missing recipient EBV serology
EBV = Epstein-Barr virus; D– = donor seronegative; R– = recipient seronegative; D+ = donor seropositive; D– = donor seronegative