Table S.1:
Adult and pediatric EBV seroprevalence among organ donors and recipients by age and sex
| Characteristics | Organ donors | Recipients | ||||
|---|---|---|---|---|---|---|
| Characteristics | n | Prevalence % (95% CI) | POR (95% CI) | n | Prevalence % (95% CI) | POR (95% CI) |
| Overall adult prevalence | 2,397* (42.1, 22.4) | 94.3 (93.3 to 95.2) | — | 3,964* (51.2, 19) | 95.8 (95.1 to 96.4) | — |
| Adult age group | ||||||
| 17–29 y | 622 | 89.5 (86.9 to 91.8) | 1.00 (Ref.) | 420 | 86.7 (83.0 to 89.8) | 1.00 (Ref.) |
| 30–39 y | 450 | 95.8a (93.5 to 97.4) | 2.65 (1.59 to 4.60) | 566 | 92.6a (90.1 to 94.6) | 1.91 (1.26 to 2.94) |
| 40–49 y | 59 | 94.9 (92.8 to 96.5) | 2.17 (1.40 to 3.45) | 874 | 97.0 (95.7 to 98.0) | 5.02 (3.13 to 8.24) |
| 50–59 y | 497 | 96.6 (94.6 to 98.0) | 3.29 (1.95 to 5.87) | 1,228 | 98.0 (97.0 to 98.7) | 7.40 (4.61 to 1.22) |
| 60–69 y | 175 | 98.3 (95.1 to 99.6) | 6.69 (2.45 to 27.60) | 792 | 97.9 (96.6 to 98.7) | 7.01 (4.11 to 1.26) |
| >70 y | 64 | 96.9 (89.2 to 99.6) | 3.62 (1.10 to 22.37) | 84 | 100 (95.7 to 100) | — |
| Adult sex | ||||||
| Male | 1,189 | 92.7 (91.1 to 94.1) | 1.00 (Ref.) | 2,608 | 95.3 (94.4 to 96.1) | 1.00 (Ref.) |
| Female | 1,208 | 95.9a (94.7 to 97.0) | 1.87 (1.31 to 2.69) | 1,356 | 96.8a (95.7 to 97.6) | 1.46 (1.04 to 2.10) |
| Overall pediatric prevalence | 239* (10.1, 11) | 74.5 (68.5 to 79.9) | — | 292* (8.1, 10) | 65.4 (59.6 to 70.9) | — |
| Pediatric age group | ||||||
| <12 mo | 54 | 72.2 (58.4 to 83.5) | — | 117 | 58.1 (48.6 to 67.2) | — |
| 12 mo–2 y | 23 | 69.6a (47.1 to 86.8) | 1 (Ref.) | 46 | 39.1a (25.9 to 54.6) | 1 (Ref.) |
| 2–4 y | 43 | 62.8 (46.7 to 77.0) | 0.74 (0.24 to 2.14) | 54 | 61.1 (46.9 to 74.1) | 2.44 (1.10 to 5.56) |
| 5–9 y | 51 | 68.6 (54.1 to 80.9) | 0.96 (0.32 to 2.73) | 64 | 59.4 (46.4 to 71.5) | 2.27 (1.06 to 5.00) |
| 10–16 y | 122 | 82.0 (74.0 to 88.3) | 1.99 (0.70 to 5.28) | 128 | 79.7 (71.7 to 86.3) | 6.10 (2.97 to 12.91) |
| Pediatric sex | ||||||
| Male | 140 | 73.6 (65.5 to 80.6) | 1 (Ref.) | 145 | 63.4 (55.1 to 71.3) | 1 (Ref.) |
| Female | 99 | 75.8 (66.1 to 83.8) | 1.12 (0.62 to 2.05) | 147 | 64.6 (56.3 to 72.3) | 1.19 (0.73 to 1.93) |
Notes: Superscript letters indicate statistically significant comparisons with p < 0.05. Pediatric patients aged less than 12 mo are included in the table to describe the seroprevalence of this group, but they were excluded from regression analysis because of the potential presence of passive maternal antibody. Dashes indicate not applicable. Boldface indicates significant at α = 0.05
* Exclusions due to missing or indeterminate serology: 226 adult donors (22 indeterminate), 224 adult recipients (34 indeterminate), 19 pediatric donors (4 indeterminate), and 16 pediatric recipients (4 indeterminate)
EBV = Epstein-Barr virus; IQR = Interquartile range; CI = Confidence interval; POR = Prevalence odds ratio; Ref. = Reference